Description

Phosphine, (6,6'-Dimethoxy[1,1'-Biphenyl]-2,2'-Diyl)Bis[Bis[3,5-Bis(Trimethylsilyl)Phenyl]-, (R)- (9Ci) is a sophisticated, chiral organophosphorus ligand of significant interest in advanced synthetic chemistry. Its value lies in its ability to act as a highly selective and efficient catalyst in asymmetric transformations, enabling the production of enantiomerically pure compounds. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for developing novel active ingredients and high-value intermediates.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric hydrogenation reactions.
• Enabling asymmetric C-C bond formation processes, such as cross-coupling and allylic substitution.
• Critical component in the synthesis of enantiomerically pure pharmaceutical intermediates, including chiral amines and alcohols.
• Use in the development of novel agrochemicals requiring specific stereochemistry for enhanced activity and safety.
• Facilitating academic and industrial research into new catalytic methodologies and reaction pathways.
• Potential applications in material science for creating chiral polymers or frameworks.

Basic Information

Product Name	Phosphine, (6,6'-Dimethoxy[1,1'-Biphenyl]-2,2'-Diyl)Bis[Bis[3,5-Bis(trimethylsilyl)phenyl]-, (R)- (9Ci)
CAS No.	150971-35-0
Molecular Formula	C58H78O2P2Si8
Molecular Weight	1084.88 g/mol
Synonyms	(R)-DTBM-SEGPHOS; (R)-3,3',5,5'-Tetra(trimethylsilyl)-4,4'-di-tert-butyl-6,6'-dimethoxy-1,1'-biphenyl-2,2'-diylbis[bis(3,5-di-tert-butylphenyl)phosphine]; (R)-DTBM-SEGPHOS Ligand; (R)-DTBM-SEGPHOS; (R)-4,4'-Bi-1,3-benzodioxole-5,5'-diylbis[bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphine] (related core structure); SEGPHOS derivative; Chiral bisphosphine ligand; Asymmetric hydrogenation ligand.
EINECS	Contact for details

Quality Control

Our high-purity chiral ligand is manufactured under controlled conditions to ensure batch-to-batch consistency and optimal catalytic performance. Each lot undergoes rigorous analytical characterization, including chiral HPLC to confirm enantiomeric excess and NMR spectroscopy for structural verification. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) in a cool, dry place. Recommended long-term storage at 2-8°C. The compound is easily oxidized and moisture-sensitive; ensure containers are sealed immediately after use to maintain integrity.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.