Description

(+)-cis-2(R),3(S)-2,3-Dihydroxy-2,3-Dihydrobenzonitrile Acetonide CAS NO 150767-96-7 is a high-purity chiral intermediate characterized by its specific stereochemistry and protected diol functionality. This compound matters for its role as a critical building block in the synthesis of complex, optically active molecules, particularly in pharmaceutical development. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), especially for drugs targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a ligand precursor or a model substrate in the development of new catalytic systems.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where specific stereoisomers are required.
• Academic & R&D: A valuable compound for methodological studies in organic synthesis and stereochemistry at universities and corporate R&D labs.

Basic Information

Product Name	(+)-cis-2(R),3(S)-2,3-Dihydroxy-2,3-Dihydrobenzonitrile Acetonide
CAS No.	150767-96-7
Molecular Formula	C₁₂H₁₃NO₃
Molecular Weight	219.24 g/mol
Synonyms	(+)-cis-2,3-O-Isopropylidene-2,3-dihydroxy-2,3-dihydrobenzonitrile; (3aR,7aS)-2,2-Dimethyl-3a,7a-dihydro-4H-[1,3]dioxolo[4,5-c]pyridine-4-carbonitrile; 2,3-Dihydroxy-2,3-dihydrobenzonitrile acetonide; (R,S)-cis-2,3-Dihydroxy-2,3-dihydrobenzonitrile acetonide; Benzonitrile, 2,3-dihydro-2,3-dihydroxy-, 2,3-acetonide, (2R-cis)-; (2R,3S)-2,3-Dihydroxy-2,3-dihydrobenzonitrile 2,3-acetonide
EINECS	Contact for details

Quality Control

Our (+)-cis-2(R),3(S)-2,3-Dihydroxy-2,3-Dihydrobenzonitrile Acetonide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, consistent with standards expected for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.