Description

H-Phe-Arg-Arg-Oh is a synthetic tripeptide derivative composed of phenylalanine and two arginine residues. This compound is valued for its role as a key intermediate and building block in advanced peptide synthesis and pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or standard in enzymatic studies, protease research, and signal transduction pathway analysis.
• Peptide Library Construction: An essential component for solid-phase and solution-phase peptide synthesis to create libraries for drug discovery screening.
• Protease Inhibitor Development: Investigated for its potential in designing and optimizing inhibitors for specific proteolytic enzymes.
• Cell Biology Studies: Employed in studies related to cell penetration, intracellular delivery, and peptide-mediated biological effects.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	H-Phe-Arg-Arg-Oh
CAS No.	150398-22-4
Molecular Formula	C21H35N9O4
Molecular Weight	477.56 g/mol
Synonyms	Phenylalanyl-arginyl-arginine; F-R-R-OH; Phe-Arg-Arg; H-Phe-Arg-Arg-OH; L-Phenylalanyl-L-arginyl-L-arginine; FRR tripeptide; (2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acid
EINECS	Contact for details

Quality Control

Our H-Phe-Arg-Arg-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.