Description

tert-Butyl n-(3-Aminopropyl)-n-Methylcarbamate is a protected amine derivative, specifically a Boc-protected aminopropyl methylamine, serving as a crucial building block in advanced organic synthesis. Its primary value lies in providing a versatile, orthogonal protecting group for primary amines, enabling selective reactions in complex multi-step sequences. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in creating molecules with aminopropyl side chains.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide chemistry to protect amine functionalities during coupling reactions.
• Agrochemical Development: Intermediate in the production of herbicides, fungicides, and insecticides that require specific amine components.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal complexes.
• Polymer Modification: Employed to introduce functional amine groups into polymer backbones for creating specialty materials with tailored properties.
• Bioconjugation Chemistry: Useful in the development of linkers and spacers for attaching molecules to proteins, antibodies, or surfaces in diagnostic and therapeutic applications.

Basic Information

Product Name	tert-Butyl n-(3-Aminopropyl)-n-Methylcarbamate
CAS No.	150349-36-3
Molecular Formula	C10H22N2O2
Molecular Weight	202.30 g/mol
Synonyms	1-[(tert-Butoxycarbonyl)(methyl)amino]-3-aminopropane; 3-[(tert-Butoxycarbonyl)(methyl)amino]propan-1-amine; N-Boc-N-methyl-1,3-propanediamine; tert-Butyl N-methyl-N-(3-aminopropyl)carbamate; Boc-N-methyl-1,3-diaminopropane; N-Methyl-N-(3-aminopropyl)carbamic acid tert-butyl ester; 3-[(tert-Butoxycarbonyl)(methyl)amino]propylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(3-Aminopropyl)-n-Methylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.