Description

(Asn670,Leu671)-Amyloid Beta/A4 Protein Precursor770 (667-675) CAS NO 150234-52-9 is a synthetic peptide fragment corresponding to a specific sequence of the amyloid precursor protein (APP). This compound is of significant value for researchers investigating the molecular mechanisms of Alzheimer's disease and related neurodegenerative disorders. It serves as a critical tool for biochemical assays, antibody development, and structure-activity relationship studies in neuroscience and pharmaceutical research.

Application

• Biochemical Research: Used as a reference standard or substrate in enzymatic studies related to APP processing.
• Antibody Production & Characterization: Acts as an immunogen or antigen for generating and testing site-specific antibodies.
• Neuroscience Studies: Employed in in vitro models to study amyloid-beta peptide formation, aggregation, and toxicity.
• Drug Discovery Screening: Utilized in high-throughput assays to identify potential therapeutic compounds that modulate APP cleavage.
• Diagnostic Development: Serves as a key component in the development of immunoassays for detecting APP metabolites.
• Academic & Pharmaceutical R&D: A fundamental reagent for basic research and pre-clinical development targeting Alzheimer's disease pathways.

Basic Information

Product Name	(Asn670,Leu671)-Amyloid Beta/A4 Protein Precursor770 (667-675)
CAS No.	150234-52-9
Molecular Formula	C46H74N12O15
Molecular Weight	1011.2 g/mol
Synonyms	APP (667-675) peptide; Amyloid Beta Precursor Protein (667-675); APP770 fragment (667-675); (Asn670,Leu671)-APP(667-675); AβPP (667-675); Amyloid Precursor Protein fragment; KEVMEDLRQ (single-letter amino acid code); Research peptide 150234-52-9
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and analyzed under stringent quality protocols to ensure high purity and batch-to-batch consistency, essential for reliable research outcomes. Each lot is accompanied by comprehensive analytical data, including mass spectrometry (MS) and high-performance liquid chromatography (HPLC) reports. Certificates of Analysis (COA) detailing purity, identity, and content are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This hygroscopic and moisture-sensitive material should be allowed to equilibrate to room temperature before opening to prevent condensation. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Within ± 10% of theoretical
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.