Description

cis-Haloperidol n-Oxide is a specific stereoisomer and oxidative metabolite of the well-known antipsychotic agent Haloperidol. This compound is of significant value as a high-purity reference standard and a critical intermediate in pharmaceutical research and development. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in neuropharmacology, drug metabolism studies, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification, purity assessment, and quantification of Haloperidol and its metabolites in analytical methods like HPLC and LC-MS.
• Metabolite Research: Serves as a key material for studying the metabolic pathways, pharmacokinetics, and pharmacodynamics of Haloperidol.
• Process Chemistry Intermediate: Employed in the research-scale synthesis and development of new Haloperidol analogs or related neuroactive compounds.
• Quality Control (QC) Testing: Essential for the validation and routine QC testing of Haloperidol active pharmaceutical ingredient (API) and finished dosage forms in GMP environments.
• Biochemical Research: Applied in *in vitro* studies to investigate receptor binding profiles and the biological activity of Haloperidol metabolites.

Basic Information

Product Name	cis-Haloperidol n-Oxide
CAS No.	150214-94-1
Molecular Formula	C21H23ClFNO3
Molecular Weight	391.87 g/mol
Synonyms	Haloperidol N-Oxide (cis-isomer); 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone N-Oxide; cis-1-(4-Fluorophenyl)-4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-butanone N-Oxide; Haloperidol cis-N-Oxide; Reduced Haloperidol N-Oxide (cis-); cis-Haloperidol N-Oxide; cis-Haloperidol 1-Oxide
EINECS	Contact for details

Quality Control

Our cis-Haloperidol n-Oxide CAS NO 150214-94-1 is manufactured under strict quality control protocols suitable for research and analytical applications. Each batch is characterized and tested to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data (e.g., by HPLC) is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.