Description

Chlorpromazine Sulphoxide n-Oxide M is a key pharmaceutical intermediate and metabolite of the antipsychotic drug chlorpromazine. This compound is of significant importance for research and development in neuropharmacology and analytical chemistry. It is primarily utilized by pharmaceutical manufacturers and research institutions for method development, impurity profiling, and metabolic studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of impurities and metabolites in chlorpromazine-based drug products.
• Metabolite Research: Critical for in vitro and in vivo studies investigating the metabolic pathways, pharmacokinetics, and pharmacodynamics of chlorpromazine.
• Analytical Method Development: Serves as a high-purity standard for calibrating HPLC, LC-MS, and other chromatographic systems in quality control laboratories.
• Impurity Profiling: Essential for establishing and validating impurity limits in accordance with ICH Q3A/B guidelines for new drug applications (NDA).
• Biochemical Research: Employed in studies exploring the biochemical mechanisms of action and potential side effects of phenothiazine derivatives.
• Process Chemistry: Used as an intermediate or marker in the synthesis and process optimization of related pharmaceutical compounds.

Basic Information

Product Name	Chlorpromazine Sulphoxide n-Oxide M
CAS No.	150111-59-4
Molecular Formula	C17H19ClN2O2S
Molecular Weight	350.86 g/mol
Synonyms	Chlorpromazine Sulfoxide N-Oxide; Chlorpromazine S-Oxide N-Oxide; 2-Chloro-10-[3-(dimethylamino)propyl]phenothiazine 5-Oxide 5-Oxide; 5-Oxido-5H-10-[3-(dimethylamino)propyl]phenothiazin-2-yl Chloride 5-Oxide; Chlorpromazine Metabolite M; CPZ Sulphoxide N-Oxide; N-Oxide of Chlorpromazine Sulfoxide; Phenothiazine-5-oxide derivative
EINECS	Contact for details

Quality Control

Our Chlorpromazine Sulphoxide n-Oxide M is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.