Description

2-Oxo-3-(Triphenylphosphoranylidene)Propanoic Acid Hydrazide is a specialized organophosphorus reagent featuring a reactive ylide and hydrazide functional group. This compound is valued for its role as a key building block in the synthesis of complex heterocyclic systems and functionalized molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A versatile synthon for the construction of nitrogen-containing heterocycles, such as pyrazoles and triazoles, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic motifs.
• Material Science Research: Serves as a precursor for creating functional organic molecules with potential applications in organic electronics or as ligands in catalysis.
• Academic & R&D Laboratories: Employed in methodological chemistry research for developing new reactions, particularly those involving Wittig-type olefination or cyclization processes.
• Peptide Mimetic Chemistry: The reactive hydrazide moiety can be utilized to create peptide analogs and conformationally restricted scaffolds for biological evaluation.

Basic Information

Product Name	2-Oxo-3-(Triphenylphosphoranylidene)Propanoic Acid Hydrazide
CAS No.	149990-86-3
Molecular Formula	C21H19N2O2P
Molecular Weight	362.36 g/mol
Synonyms	3-(Triphenylphosphoranylidene)pyruvic acid hydrazide; (Triphenylphosphoranylidene)pyruvic acid hydrazide; 2-Oxo-3-(triphenyl-λ5-phosphanylidene)propanehydrazide; Pyruvic acid, 3-(triphenylphosphoranylidene)-, hydrazide; 149990-86-3; (Carboxyformylmethylene)triphenylphosphorane hydrazide
EINECS	Contact for details

Quality Control

Our 2-Oxo-3-(Triphenylphosphoranylidene)Propanoic Acid Hydrazide is produced under controlled conditions to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.