Description

tert-Butyl But-3-Yn-1-Ylcarbamate is a protected alkyne-containing amine derivative, serving as a versatile and high-purity synthetic building block. Its primary value lies in enabling the controlled introduction of a terminal alkyne functional group into complex molecular architectures under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for applications in click chemistry, peptide modification, and polymer synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, especially those utilizing alkyne-azide cycloaddition (click chemistry) for bioconjugation.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that require alkyne functionality.
• Peptide Chemistry: Enables site-specific labeling and modification of peptides and proteins via the incorporation of a protected alkyne handle.
• Polymer & Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers, dendrimers, and smart materials with tailored properties.
• Chemical Biology Probes: Integral for developing molecular probes and diagnostic tools that rely on bioorthogonal labeling strategies.
• Organic Synthesis: A versatile reagent for constructing complex organic molecules, including natural products and heterocycles, through Sonogashira and other cross-coupling reactions.

Basic Information

Product Name	tert-Butyl But-3-Yn-1-Ylcarbamate
CAS No.	149990-27-2
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	N-Boc-3-butyn-1-amine; tert-Butyl (3-butyn-1-yl)carbamate; Boc-3-butyn-1-amine; 3-Butyn-1-amine, N-Boc-protected; But-3-yn-1-ylcarbamic acid tert-butyl ester; 1-Boc-amino-3-butyne; N-(tert-Butoxycarbonyl)-3-butyn-1-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl But-3-Yn-1-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.