Description

1-Acetamido-2-(4-Fluorophenyl)Ethane-1-Boronic Acid is a specialized boronic acid derivative that serves as a crucial building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a protected amine moiety, enabling precise molecular construction. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to create biaryl structures, a common motif in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides and fungicides with enhanced efficacy and selectivity.
• Ligand Synthesis: Serves as a precursor for creating novel ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and protein interactions.
• Advanced Material Development: Incorporated into polymers and organic electronic materials to modify their properties.

Basic Information

Product Name	1-Acetamido-2-(4-Fluorophenyl)Ethane-1-Boronic Acid
CAS No.	149982-17-2
Molecular Formula	C10H13BFNO3
Molecular Weight	225.03 g/mol
Synonyms	N-[2-(4-Fluorophenyl)-1-(hydroxyboranyl)ethyl]acetamide; 2-(4-Fluorophenyl)-1-(hydroxyboranyl)ethyl Acetamide; 1-Acetamido-2-(4-fluorophenyl)ethylboronic Acid; (1-Acetamido-2-(4-fluorophenyl)ethyl)boronic Acid; 4-Fluorophenethylboronic Acid Acetamide Derivative; B-[1-Acetamido-2-(4-fluorophenyl)ethyl]boronic Acid
EINECS	Contact for details

Quality Control

Our 1-Acetamido-2-(4-Fluorophenyl)Ethane-1-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.