Description

2-Methyl-5-Trifluoromethyl-2H-Pyrazol-3-Ylamine is a high-purity, heterocyclic amine building block of significant importance in advanced organic synthesis. Its core value lies in its trifluoromethylated pyrazole structure, which is highly sought after for imparting desirable metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, serving as a critical intermediate for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Research: Employed as a building block for novel organic ligands, catalysts, and functional polymers with specialized electronic or surface properties.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes, enzyme inhibitors, and tool compounds for biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, fluorinated molecules for clients.

Basic Information

Product Name	2-Methyl-5-Trifluoromethyl-2H-Pyrazol-3-Ylamine
CAS No.	149978-43-8
Molecular Formula	C5H6F3N3
Molecular Weight	165.12 g/mol
Synonyms	5-(Trifluoromethyl)-2-methyl-2H-pyrazol-3-amine; 3-Amino-2-methyl-5-(trifluoromethyl)pyrazole; 2-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-amine; 2-Methyl-5-(trifluoromethyl)pyrazol-3-ylamine; 5-Trifluoromethyl-2-methyl-2H-pyrazol-3-amine; 149978-43-8; 2-Methyl-5-trifluoromethylpyrazol-3-amine
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-Trifluoromethyl-2H-Pyrazol-3-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.