Description

1,3-Bis(Di-T-Butylphosphinomethyl)Benzene is a specialized, high-value organophosphorus ligand used in advanced catalytic processes. This compound is critical for enabling highly selective and efficient cross-coupling reactions in fine chemical and pharmaceutical synthesis. It is primarily required by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic pathways and optimizing production of complex molecules.

Application

• Homogeneous Catalysis: As a key ligand in palladium- and nickel-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Buchwald-Hartwig aminations.
• Pharmaceutical Intermediate Synthesis: For the efficient and selective construction of carbon-carbon and carbon-heteroatom bonds in active pharmaceutical ingredient (API) manufacturing.
• Agrochemical Production: In the synthesis of complex, biologically active molecules for crop protection agents.
• Material Science Research: For the development of novel polymers and functional materials via metal-mediated polymerization or functionalization.
• Asymmetric Synthesis: Potential use in creating chiral variants for enantioselective catalytic transformations.
• Catalyst Screening & Optimization: A valuable tool in high-throughput experimentation (HTE) for discovering new catalytic systems in industrial R&D.

Basic Information

Product Name	1,3-Bis(Di-T-Butylphosphinomethyl)Benzene
CAS No.	149968-36-5
Molecular Formula	C24H44P2
Molecular Weight	394.55 g/mol
Synonyms	1,3-Bis[bis(tert-butylphosphino)methyl]benzene; 1,3-Bis(di-tert-butylphosphanylmethyl)benzene; Di-T-Butylphosphinomethyl Benzene Derivative; DTBPMB; (1,3-Phenylene)bis(methylene)bis(di-tert-butylphosphine); Bisphosphine Ligand
EINECS	Contact for details

Quality Control

Our production of 1,3-Bis(Di-T-Butylphosphinomethyl)Benzene adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, which is essential for catalytic performance. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be purged with inert gas after each opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
31P NMR Purity	Conforms
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.