Description

Drosocin CAS NO 149924-99-2 is a synthetic antimicrobial peptide (AMP) analog, designed to mimic the structure and function of natural insect-derived defensins. This compound is of significant interest for its potent activity against a broad spectrum of Gram-negative bacteria, including multi-drug resistant strains. It serves as a critical research tool and a promising lead compound for pharmaceutical development in the fields of anti-infective therapeutics, immunology research, and novel antibiotic discovery.

Application

• Biomedical Research: Fundamental studies on innate immunity, peptide-membrane interactions, and mechanisms of bacterial lysis.
• Antimicrobial Agent Development: As a lead structure for designing new classes of antibiotics to combat antibiotic-resistant pathogens.
• In Vitro Assays: Used in high-throughput screening (HTS) platforms to evaluate bacterial susceptibility and synergy with conventional antibiotics.
• Biomaterial Coating: Research into surface functionalization for medical devices and implants to prevent biofilm formation.
• Veterinary Medicine: Investigation of novel therapeutic agents for animal health, particularly against challenging Gram-negative infections.
• Cell Culture & Microbiology: As a selective agent in specialized microbial culture media or in studies of host-pathogen interactions.

Basic Information

Product Name	Drosocin
CAS No.	149924-99-2
Molecular Formula	C95H147N31O31
Molecular Weight	~2190.37 g/mol
Synonyms	Drosocin peptide; Antimicrobial peptide Drosocin; DRS; Drosophila-derived antimicrobial peptide; Glycosylated proline-rich antimicrobial peptide; GKPRPYSPRPTSHPRPIRV (sequence); CG10850-PA (Drosophila gene product); Proline-rich antibacterial peptide.
EINECS	Contact for details

Quality Control

Our Drosocin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and biological activity. We provide full traceability and detailed Certificates of Analysis (COA) that include data from HPLC, MS, and amino acid analysis. Our quality commitment aligns with the standards required for research-grade biochemicals and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.