Description

Tiludronic Acid, Disodium Salt CAS NO 149845-07-8 is a high-purity bisphosphonate compound, serving as a key active pharmaceutical ingredient (API) and a critical research chemical. This compound is valued for its potent and specific biological activity, making it essential for the development of advanced therapeutic and diagnostic agents. It is primarily required by pharmaceutical manufacturers, biotechnology research institutions, and advanced material science laboratories.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of bisphosphonate drugs for the treatment of bone disorders such as Paget's disease and osteoporosis.
• Biomedical Research: Used as a reference standard and biochemical tool in studies of bone metabolism, osteoclast inhibition, and calcium regulation pathways.
• Veterinary Medicine: Applied in the development of treatments for skeletal diseases in companion and large animals.
• Chemical Synthesis: Serves as a crucial intermediate or precursor for the synthesis of novel bisphosphonate derivatives and targeted drug conjugates.
• Diagnostic Agent Development: Utilized in the research and formulation of bone-imaging agents and radiopharmaceuticals.

Basic Information

Product Name	Tiludronic Acid, Disodium Salt
CAS No.	149845-07-8
Molecular Formula	C7H6ClNa2O6P2S
Molecular Weight	377.06 g/mol
Synonyms	Tiludronate Disodium; Tiludronic Acid Disodium Salt; (4-Chlorophenyl)thio-methylene-1,1-bisphosphonic Acid Disodium Salt; SR 41319B; CAS 149845-07-8; Tiludronate; Disodium Tiludronate
EINECS	Contact for details

Quality Control

Our Tiludronic Acid, Disodium Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and stringent control of residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with cGMP and relevant pharmacopeial guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.