Description

Acetamide, n-5-(1,2-Dihydroxyethyl)-4-Hydroxy-3-Pyrrolidinyl-, Monohydrochloride, 3S-3.Alpha.,4.Beta.,5.Alpha.(R*)- is a high-purity, stereochemically defined pyrrolidine derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the construction of complex molecules with precise three-dimensional architecture. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly those targeting neurological and metabolic pathways. CAS No. 149818-01-9.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Biochemical Research: Employed in studies of enzyme inhibition and receptor binding due to its complex, polyfunctional structure mimicking natural substrates.
• Fine Chemical Manufacturing: Utilized in custom synthesis and contract manufacturing for producing high-value, specialty chemicals.
• Academic & Institutional Research: A valuable compound for methodological development in synthetic organic chemistry and stereochemistry studies.

Basic Information

Product Name	Acetamide, n-5-(1,2-Dihydroxyethyl)-4-Hydroxy-3-Pyrrolidinyl-, Monohydrochloride, 3S-3.Alpha.,4.Beta.,5.Alpha.(R*)-
CAS No.	149818-01-9
Molecular Formula	C8H16N2O4 • HCl
Molecular Weight	248.69 g/mol (Free base: 212.22 g/mol)
Synonyms	(3S,4R,5R)-1-[(2R)-2,3-Dihydroxypropyl]-4-hydroxy-3-(hydroxymethyl)pyrrolidine-5-carboxamide hydrochloride; 1-Deoxynojirimycin derivative hydrochloride; Dihydroxypropyl-DNJ HCl; 3-O-β-D-Glucopyranosyl-1-deoxynojirimycin analog; α-HomoDMDP derivative; Polyhydroxylated pyrrolidine amide hydrochloride; (3S,4R,5R)-5-(Aminocarbonyl)-1-[(2R)-2,3-dihydroxypropyl]-3,4-dihydroxypyrrolidinium chloride
EINECS	Contact for details

Quality Control

Our Acetamide, n-5-(1,2-Dihydroxyethyl)-4-Hydroxy-3-Pyrrolidinyl-, Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis for stereochemical integrity, and residual solvent analysis to ensure it meets exacting research and development standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.