Description

Frizzled-1 Protein, Vertebrate is a high-purity, recombinant protein that plays a critical role in the Wnt signaling pathway, a fundamental process in cellular development and regulation. This protein is essential for research and development in targeted drug discovery and molecular biology studies. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in oncology, regenerative medicine, and developmental biology research.

Application

• Biochemical Research: Used as a key reagent in studying the structure, function, and activation mechanisms of the Frizzled receptor family and the Wnt signaling cascade.
• Drug Discovery & Screening: Serves as a target protein in high-throughput screening (HTS) assays to identify and validate novel therapeutic compounds, particularly for cancer and metabolic diseases.
• Antibody Production & Validation: Acts as an immunogen for generating specific monoclonal or polyclonal antibodies used in diagnostic and therapeutic applications.
• Cell Signaling Studies: Employed in in vitro cell-based assays to investigate ligand-receptor interactions, pathway modulation, and downstream gene expression effects.
• Protein-Protein Interaction Analysis: Utilized in techniques such as surface plasmon resonance (SPR) or pull-down assays to map interaction networks within the Wnt pathway.
• Academic & Institutional Research: Supports fundamental research in developmental biology, stem cell differentiation, and tissue homeostasis.

Basic Information

Product Name	Frizzled-1 Protein, Vertebrate
CAS No.	149748-09-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	FZD1 Protein; Frizzled-1 Receptor; hFZD1; Frizzled homolog 1; Fz-1; FzE1; Frizzled, Drosophila, Homolog Of, 1; CD344
EINECS	Contact for details

Quality Control

Our Frizzled-1 Protein, Vertebrate is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous quality testing, including purity analysis, endotoxin level checks, and functional activity assays. Certificates of Analysis (COA) detailing specific results for purity, identity, and activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed properly after each use to prevent degradation.

Specification

Item	Specification
Appearance	Lyophilized powder or clear solution
Purity (SDS-PAGE)	> 95%
Identification (Mass Spec)	Conforms
Endotoxin Level	< 1.0 EU/µg
Biological Activity (Cell-based assay)	Confirmed
Protein Concentration	Provided on COA
Buffer Composition	Provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.