Description

2-(3-Indolylmethyl)-L-Tryptophan CAS NO 149724-31-2 is a specialized, high-purity tryptophan derivative with significant potential in advanced biochemical research and pharmaceutical development. This compound matters for its role as a key intermediate or reference standard in the synthesis of complex peptides and the study of indole-based metabolic pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on neurochemistry, peptide mimetics, and novel therapeutic agent discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel peptide-based drugs and bioactive molecules targeting neurological pathways.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies, metabolic pathway analysis, and receptor-ligand interaction research.
• Peptide Synthesis: Acts as a specialized amino acid derivative for the solid-phase or solution-phase synthesis of complex peptides with enhanced properties.
• Neuroscience Studies: Employed in research investigating serotonin-related pathways, tryptophan metabolism, and the function of indolealkylamines.
• Analytical Standard: Provides a high-purity standard for method development and quality control in HPLC, LC-MS, and other analytical techniques within QC laboratories.
• Fine Chemical Production: Utilized as a precursor for manufacturing other high-value, specialized indole derivatives and chiral compounds.

Basic Information

Product Name	2-(3-Indolylmethyl)-L-Tryptophan
CAS No.	149724-31-2
Molecular Formula	C21H21N3O2
Molecular Weight	347.41 g/mol
Synonyms	L-Tryptophan, 2-[(1H-indol-3-yl)methyl]-; 2-(Indol-3-ylmethyl)tryptophan; 2-(1H-Indol-3-ylmethyl)-L-tryptophan; (S)-2-((1H-Indol-3-yl)methyl)tryptophan; 2-(3-Indolylmethyl)tryptophan; Bis-tryptophan derivative; Tryptophan dimer analog; 149724-31-2
EINECS	Contact for details

Quality Control

Our 2-(3-Indolylmethyl)-L-Tryptophan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC. Certificates of Analysis (COA) detailing specific results for identity, assay, and related substances are available upon request to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.