Description

Caveolin-1 CAS NO 149720-12-7 is a key structural and regulatory protein that forms the primary component of caveolae, specialized lipid rafts in the plasma membrane. Its critical role in cellular signaling, cholesterol homeostasis, and endocytosis makes it an essential research tool for understanding cell biology and disease mechanisms. This high-purity biochemical is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic developers focusing on cardiovascular disease, cancer biology, and metabolic disorders.

Application

• Biomedical Research: Fundamental studies on caveolae structure, membrane dynamics, and cellular signaling pathways.
• Drug Discovery & Target Validation: Used in assays to identify and validate novel therapeutic targets related to caveolin-1 function in diseases like cancer and atherosclerosis.
• Antibody Production & Immunoassays: Serves as a high-quality antigen for generating specific monoclonal and polyclonal antibodies for Western blotting, ELISA, and immunohistochemistry.
• Cell Biology & Biochemistry: Investigation of protein-protein interactions, lipid raft composition, and the role of caveolin-1 in mechanotransduction and endocytosis.
• Diagnostic Development: Potential use as a reference standard or component in developing diagnostic tests for conditions where caveolin-1 expression is a biomarker.

Basic Information

Product Name	Caveolin-1
CAS No.	149720-12-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Caveolin 1; CAV1; Caveolae-associated protein 1; VIP21; MGC102859; MSTP085; BSCL3; LCCNS; PPH3; CAV; Caveolin; Caveolin-1, human; Caveolin-1 protein; Caveolin-1 (22-178)
EINECS	Contact for details

Quality Control

Our Caveolin-1 is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation by mass spectrometry, and functional activity checks. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For extended storage, consider aliquoting to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Conforms
Purity (SDS-PAGE)	≥ 95%
Purity (HPLC)	≥ 98.0%
Endotoxin Level	< 1.0 EU/μg
Biological Activity	Confirmed by functional assay
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.