Description

2-(4-Bromophenyl)-n-Methoxy-n-Methylacetamide is a specialized organic building block featuring a brominated phenyl ring and an N-methoxy-N-methylamide (Weinreb amide) group. This compound is of significant value in synthetic organic chemistry, primarily serving as a versatile intermediate for the controlled synthesis of ketones and other carbonyl derivatives. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in complex molecule construction and API development.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly those requiring aryl ketone motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the bromophenyl moiety is a critical structural component.
• Weinreb Amide Applications: Exploits its role as a Weinreb amide for the selective and high-yield preparation of ketones from organometallic reagents like Grignard or organolithium compounds.
• Material Science Research: Serves as a building block for creating organic ligands, monomers, or advanced organic materials with specific electronic properties.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploratory synthesis in university and industrial research settings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring this precise chemical handle.

Basic Information

Product Name	2-(4-Bromophenyl)-n-Methoxy-n-Methylacetamide
CAS No.	149652-50-6
Molecular Formula	C10H12BrNO2
Molecular Weight	258.11 g/mol
Synonyms	N-Methoxy-N-methyl-2-(4-bromophenyl)acetamide; 2-(4-Bromophenyl)-N-methoxy-N-methylacetamide; 4-Bromophenylacetic acid N-methoxy-N-methylamide; N-Methoxy-N-methyl-4-bromophenylacetamide; Weinreb amide of 4-Bromophenylacetic acid; α-(4-Bromophenyl)-N-methoxy-N-methylacetamide
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Bromophenyl)-n-Methoxy-n-Methylacetamide is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. We provide comprehensive analytical data including HPLC purity, NMR confirmation, and identity verification. A Certificate of Analysis (COA) detailing all specifications is available with each shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.