Description

D-Glucitol, 2-(Acetylamino)-2-Deoxy-5,6-o-(1-Methylethylidene)-3-o-(Phenylmethyl)- is a sophisticated, protected sugar derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its precisely defined stereochemistry and protective groups, which enable the controlled construction of complex bioactive molecules. This high-purity intermediate is essential for research and development in the pharmaceutical and fine chemical industries, particularly for the synthesis of novel glycosidase inhibitors, antiviral agents, and other therapeutic compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of glycosidase inhibitors and antiviral drugs.
• Carbohydrate Chemistry Research: Used in academic and industrial R&D for studying glycosylation reactions and synthesizing complex oligosaccharides.
• Fine Chemical Synthesis: Serves as a building block for creating specialized surfactants, ligands, and other value-added chemical products.
• Glycoconjugate Development: Employed in the synthesis of glycopeptides, glycolipids, and other biologically active conjugates for diagnostic and therapeutic applications.
• Process Chemistry: Used in scaling up synthetic routes for active pharmaceutical ingredients (APIs) that require specific sugar-based motifs.

Basic Information

Product Name	D-Glucitol, 2-(Acetylamino)-2-Deoxy-5,6-o-(1-Methylethylidene)-3-o-(Phenylmethyl)-
CAS No.	149625-48-9
Molecular Formula	C18H25NO6
Molecular Weight	351.40 g/mol
Synonyms	3-O-Benzyl-5,6-O-isopropylidene-2-acetamido-2-deoxy-D-glucitol; 2-Acetamido-2-deoxy-5,6-O-isopropylidene-3-O-benzyl-D-glucitol; 2-Acetamido-1,2-dideoxy-5,6-O-(1-methylethylidene)-3-O-(phenylmethyl)-D-glucitol; Protected N-Acetyl-D-glucosaminitol derivative; Benzyl-protected glucitol intermediate; Isopropylidene acetal of N-Acetyl-D-glucosaminitol.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high chemical purity, suitable for demanding synthetic applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and optical rotation analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.