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D-Phenylalanine, β-Phenyl-n-[(Phenylmethoxy)Carbonyl]- CAS NO 149597-95-5


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CAS No.:149597-95-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

D-Phenylalanine, β-Phenyl-n-[(Phenylmethoxy)Carbonyl]- is a protected derivative of the non-natural D-enantiomer of the essential amino acid phenylalanine. This compound is of significant value as a key chiral building block and intermediate in sophisticated organic synthesis, particularly in the pharmaceutical and peptide research sectors. It is primarily needed by R&D chemists and process development scientists working on the synthesis of novel peptides, peptidomimetics, and active pharmaceutical ingredients (APIs) where stereochemical purity is critical.

Application

  • Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel therapeutic peptides and peptidomimetic drugs.
  • Peptide Chemistry Research: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-phenylalanine residues with a protected side chain.
  • Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecules with high enantiomeric excess.
  • Biochemical Research: Employed in studies of enzyme specificity, receptor-ligand interactions, and metabolic pathways involving D-amino acids.
  • Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name D-Phenylalanine, β-Phenyl-n-[(Phenylmethoxy)Carbonyl]-
CAS No. 149597-95-5
Molecular Formula C17H17NO3
Molecular Weight 283.32 g/mol
Synonyms N-Carbobenzoxy-D-phenylalanine; N-Cbz-D-Phenylalanine; Z-D-Phe-OH; (R)-2-((((Benzyloxy)carbonyl)amino)-3-phenylpropanoic acid; D-N-Carbobenzoxyphenylalanine; D-Phenylalanine, N-[(phenylmethoxy)carbonyl]-; N-Benzyloxycarbonyl-D-phenylalanine; CBZ-D-Phenylalanine
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Quality Control

Our D-Phenylalanine, β-Phenyl-n-[(Phenylmethoxy)Carbonyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Enantiomeric Purity (Chiral HPLC) ≥99.0% ee
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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