Description

(Z)-1-Bromo-3,3,3-Trifluoroprop-1-Ene is a high-value organofluorine building block characterized by its bromoalkene and trifluoromethyl functionalities. This compound is essential for introducing the versatile CF3 group into complex molecular architectures via cross-coupling and addition reactions. It is primarily sought after by R&D and process chemists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates, active ingredients, and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing trifluoromethylated bioactive molecules, including potential APIs for oncology, CNS, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and environmental stability.
• Material Science: Serves as a monomer or precursor for specialty polymers, liquid crystals, and organic electronic materials with tailored properties.
• Cross-Coupling Reactions: Acts as an effective coupling partner in Heck, Suzuki, and Sonogashira reactions to create complex, fluorinated olefins.
• Nucleophilic Addition Substrate: The electron-deficient alkene is receptive to nucleophilic attack, enabling the synthesis of various functionalized trifluoromethyl compounds.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and reaction pathways.

Basic Information

Product Name	(Z)-1-Bromo-3,3,3-Trifluoroprop-1-Ene
CAS No.	149597-48-8
Molecular Formula	C3H2BrF3
Molecular Weight	174.95 g/mol
Synonyms	(Z)-3-Bromo-1,1,1-trifluoropropene; (Z)-1-Bromo-3,3,3-trifluoropropene; (Z)-3,3,3-Trifluoro-1-bromopropene; 1-Bromo-3,3,3-trifluoro-(Z)-prop-1-ene; trans-1-Bromo-3,3,3-trifluoropropene (common misassignment); 3-Bromo-1,1,1-trifluoro-(Z)-propene; Bromotrifluoropropene (Z-isomer); BTP (Z-isomer)
EINECS	Contact for details

Quality Control

Every batch of (Z)-1-Bromo-3,3,3-Trifluoroprop-1-Ene undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of process chemistry and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity by GC/HPLC, isomer content, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
(Z)-Isomer Content	≥ 95.0% (by GC)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.