Description

Unc-5 Protein CAS NO 149592-60-9 is a high-purity recombinant protein that plays a critical role in neuronal guidance and apoptosis signaling pathways. This product is essential for researchers and developers in life sciences requiring a reliable and well-characterized reagent for advanced cellular and molecular studies. It is primarily utilized in neuroscience research, drug discovery for neurodegenerative diseases, and as a key component in biochemical assay development.

Application

• Neuroscience Research: Used as a critical reagent to study axon guidance, neuronal migration, and the development of the nervous system.
• Apoptosis Studies: Employed in research focused on programmed cell death mechanisms, particularly in cancer and developmental biology.
• Drug Discovery & Screening: Serves as a target protein in high-throughput screening assays for identifying potential therapeutics for neurodegenerative conditions and cancer.
• Biochemical Assay Development: Utilized as a standard or coating protein in ELISA, protein-protein interaction studies, and other in vitro diagnostic applications.
• Cell Signaling Pathway Analysis: Applied in research to elucidate the Netrin signaling pathway and its role in various physiological and pathological processes.
• Recombinant Protein Production: Acts as a reference material for quality control in the production of other recombinant proteins and biologics.

Basic Information

Product Name	Unc-5 Protein
CAS No.	149592-60-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	UNC5A; UNC5H1; p53-Regulated Receptor for Death in Cancer 1; p53RDL1; Netrin Receptor UNC5A; Unc-5 Homolog A; UNC5H1 Receptor; Protein Unc-5 Homolog A; Dependence Receptor UNC5A
EINECS	Contact for details

Quality Control

Our Unc-5 Protein is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, endotoxin level determination, and functional activity verification. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the vial is equilibrated to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Purity (SDS-PAGE)	≥ 95%
Identification (Mass Spec)	Conforms
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Cell-based assay)	Reported on COA
Protein Concentration	Reported on COA
Solubility	Reconstitutes in PBS or specified buffer
Formulation	Lyophilized from sterile-filtered solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.