Description

(5S)-5-(Hydroxydiphenylmethyl)-2-Pyrrolidinone CAS NO 149561-81-9 is a high-purity chiral intermediate belonging to the pyrrolidinone class of compounds. Its value lies in its role as a critical building block for the synthesis of complex, biologically active molecules, particularly in the pharmaceutical sector. This product is essential for research and development chemists and process engineers working in pharmaceutical manufacturing, fine chemical synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder drugs.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in stereoselective chemical reactions to introduce specific chiral centers.
• Fine Chemical Production: Serves as a building block for creating complex organic molecules in custom synthesis and contract manufacturing.
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and developing novel therapeutic candidates.
• Ligand and Catalyst Development: Potential use in the design of novel chiral ligands or organocatalysts for catalytic processes.

Basic Information

Product Name	(5S)-5-(Hydroxydiphenylmethyl)-2-Pyrrolidinone
CAS No.	149561-81-9
Molecular Formula	C17H17NO2
Molecular Weight	267.32 g/mol
Synonyms	(5S)-5-(Hydroxydiphenylmethyl)-2-pyrrolidinone; (S)-5-(Hydroxydiphenylmethyl)-2-pyrrolidinone; 5-(Hydroxydiphenylmethyl)-2-pyrrolidinone, (5S)-; (S)-5-(α-Hydroxybenzhydryl)-2-pyrrolidinone; (S)-Levetiracetam Impurity; 2-Pyrrolidinone, 5-(hydroxydiphenylmethyl)-, (5S)-; 149561-81-9
EINECS	Contact for details

Quality Control

Our (5S)-5-(Hydroxydiphenylmethyl)-2-Pyrrolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.