Description

(R)-2-n-Boc-Aminocyclohexanone is a high-purity chiral building block and protected amino ketone derivative essential for advanced organic synthesis. This compound is critical for the stereoselective construction of complex molecules, offering researchers precise control over molecular architecture. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Peptidomimetics Research: Serves as a constrained scaffold for designing and synthesizing novel peptide analogs with enhanced metabolic stability.
• Asymmetric Catalysis: Used as a precursor for chiral ligands or catalysts in enantioselective transformations.
• Agrochemical Synthesis: Employed in the research and development of chiral pesticides and herbicides.
• Academic & Institutional R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for the production of bespoke fine chemicals and advanced intermediates under cGMP or ISO standards.

Basic Information

Product Name	(R)-2-n-Boc-Aminocyclohexanone
CAS No.	149524-64-1
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)cyclohexan-1-one; (R)-2-(Boc-amino)cyclohexanone; (R)-N-Boc-2-aminocyclohexanone; (R)-2-Amino-1-cyclohexanone, N-Boc derivative; tert-Butyl (R)-(2-oxocyclohexyl)carbamate; (R)-Boc-ACH; (1R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]cyclohexan-1-one
EINECS	Contact for details

Quality Control

Our (R)-2-n-Boc-Aminocyclohexanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.