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3-Trifluoromethyl-4-Methoxy-Phenylboronic Acid CAS NO 149507-36-8


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CAS No.:149507-36-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Trifluoromethyl-4-Methoxy-Phenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound is a critical intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient formation of carbon-carbon bonds. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl and methoxy pharmacophores.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
  • Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes.
  • Polymer Chemistry: Employed to introduce functional aromatic groups into polymer backbones, modifying material properties.
  • Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
  • Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name 3-Trifluoromethyl-4-Methoxy-Phenylboronic Acid
CAS No. 149507-36-8
Molecular Formula C8H8BF3O3
Molecular Weight 219.96 g/mol
Synonyms (3-(Trifluoromethyl)-4-methoxyphenyl)boronic acid; 4-Methoxy-3-(trifluoromethyl)benzeneboronic acid; 3-Trifluoromethyl-4-methoxybenzeneboronic acid; (4-Methoxy-3-trifluoromethylphenyl)boronic acid; Boronic acid, B-[3-(trifluoromethyl)-4-methoxyphenyl]-; 3-CF3-4-MeO-C6H3-B(OH)2
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results from HPLC, NMR, and other analytical methods are available upon request. We adhere to strict in-house quality protocols to guarantee the reliability required for sensitive applications like pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0%
Water Content (KF) ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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