Description

3-Fluoro-4-Methoxybenzeneboronic Acid is a versatile and high-purity boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to synthesize complex fluorinated and methoxylated aromatic structures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aryl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorine and methoxy substituents impart specific biological activity.
• Material Science & OLED Development: Building block for constructing complex organic molecules used in organic light-emitting diodes (OLEDs), liquid crystals, and electronic materials.
• Ligand & Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and bioconjugates for diagnostic and research applications.
• Academic & Contract Research: Fundamental reagent for methodological development and discovery chemistry in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	3-Fluoro-4-Methoxybenzeneboronic Acid
CAS No.	149507-26-6
Molecular Formula	C7H8BFO3
Molecular Weight	169.95 g/mol
Synonyms	(3-Fluoro-4-methoxyphenyl)boronic acid; 3-Fluoro-4-methoxybenzeneboronic acid; 3-Fluoro-4-methoxy-phenylboronic acid; 4-Methoxy-3-fluorobenzeneboronic acid; 3-Fluoro-4-methoxybenzeneboronic acid pinacol ester (common derivative); 3-Fluoro-p-anisylboronic acid; Boronic acid, B-(3-fluoro-4-methoxyphenyl)-; 149507-26-6
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methoxybenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and 1H/11B/19F NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling reactions. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment, ensuring full traceability and compliance with research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.