Description

Cdr-H3/C2 H-Cys-Asp-Leu-Ile-Tyr-Tyr-Asp-Tyr-Glu-Glu-Asp-Tyr-Tyr-Phe-Asp-Cys-Oh (Disulfide Bond) is a synthetic peptide featuring a critical intramolecular disulfide bridge that stabilizes its bioactive conformation. This compound is of significant interest for its role in advanced biochemical research and therapeutic development, particularly in immunology and signal transduction studies. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide-based drug discovery and molecular biology applications.

Application

• Biochemical Research: Used as a reference standard or active component in studies of protein-protein interactions and cellular signaling pathways.
• Immunology Studies: Serves as a potential antigen or epitope mimic for investigating immune responses and antibody development.
• Drug Discovery: A key intermediate or lead compound in the development of novel peptide-based therapeutics targeting specific receptors.
• Diagnostic Development: Employed in the design and validation of diagnostic assays, including ELISA tests, for detecting specific biomarkers.
• Structural Biology: Utilized in NMR and X-ray crystallography studies to understand the relationship between peptide structure and function.
• Cell Biology: Applied in cell culture experiments to study the effects of specific peptide sequences on cell proliferation, differentiation, or apoptosis.

Basic Information

Product Name	Cdr-H3/C2 H-Cys-Asp-Leu-Ile-Tyr-Tyr-Asp-Tyr-Glu-Glu-Asp-Tyr-Tyr-Phe-Asp-Cys-Oh (Disulfide Bond)
CAS No.	149475-21-8
Molecular Formula	C106H138N20O38S2
Molecular Weight	2356.5 g/mol (theoretical)
Synonyms	CDR-H3/C2 Peptide; Complementarity-Determining Region H3/C2 Peptide; Cyclic Cdr-H3/C2 Peptide; H-Cys-Asp-Leu-Ile-Tyr-Tyr-Asp-Tyr-Glu-Glu-Asp-Tyr-Tyr-Phe-Asp-Cys-OH (Disulfide); Cys-Asp-Leu-Ile-Tyr-Tyr-Asp-Tyr-Glu-Glu-Asp-Tyr-Tyr-Phe-Asp-Cys (Disulfide); Antibody CDR-Derived Peptide; Synthetic Immunoglobulin Peptide Fragment
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of Cdr-H3/C2 peptide undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research-grade standards and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store the lyophilized powder under desiccant. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ± 10% of theoretical
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.