Description

Boc-D-Cysteine (Boc-D-Cys-OH) is a high-purity, protected derivative of the non-natural D-enantiomer of the amino acid cysteine. This compound is a critical chiral building block in peptide synthesis, offering precise stereochemical control for the development of novel pharmaceuticals and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require high-fidelity, enantiomerically pure intermediates for drug discovery and development.

Application

• Pharmaceutical Peptide Synthesis: As a key chiral intermediate for incorporating the D-cysteine moiety into therapeutic peptides, enhancing stability and biological activity.
• Proteomics Research: Used in the study of protein structure and function, particularly for introducing specific disulfide bonds or modifications using the D-enantiomer.
• Bioconjugation & Labeling: The protected thiol group allows for site-specific conjugation in the development of antibody-drug conjugates (ADCs) and diagnostic probes.
• Combinatorial Chemistry: Serves as a valuable building block in libraries for high-throughput screening of new drug candidates.
• Material Science: Potential use in creating chiral surfaces or polymers with specific molecular recognition properties.

Basic Information

Product Name	Boc-D-Cysteine (Boc-D-Cys-OH)
CAS No.	149270-12-2
Molecular Formula	C8H15NO4S
Molecular Weight	221.27 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-3-mercaptopropanoic acid; D-Cysteine, N-(tert-butoxycarbonyl)-; Boc-D-Cys-OH; N-Boc-D-cysteine; N-tert-Butoxycarbonyl-D-cysteine; BOC-D-Cysteine; tert-Butyloxycarbonyl-D-cysteine; (R)-2-(Boc-amino)-3-sulfanylpropanoic acid
EINECS	Contact for details

Quality Control

Our Boc-D-Cysteine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistent quality, lot-to-lot traceability, and compliance with relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0% (D-enantiomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.