Description

Hippocalcin CAS NO 149223-81-4 is a high-purity calcium-binding protein that plays a critical role in neuronal calcium signaling and neuroprotection. This compound is essential for researchers and developers in the life sciences sector, particularly for studying intracellular calcium dynamics and related neurological pathways. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in neuroscience and drug discovery.

Application

• Neuroscience Research: A key reagent for studying calcium-mediated signal transduction, synaptic plasticity, and neuronal excitability.
• Drug Discovery & Development: Used as a target or biomarker in screening assays for novel therapeutics targeting neurodegenerative diseases.
• Biochemical Assays: Serves as a standard or component in ELISA, Western Blot, and other protein interaction studies.
• Cellular & Molecular Biology: Employed in cell culture studies to investigate the role of calcium sensors in apoptosis and cell survival mechanisms.
• Diagnostic Development: Potential use in the development of diagnostic tools for conditions involving calcium signaling dysregulation.

Basic Information

Product Name	Hippocalcin
CAS No.	149223-81-4
Molecular Formula	C20H32N4O4
Molecular Weight	392.5 g/mol
Synonyms	Hippocalcin; Neuronal calcium sensor protein hippocalcin; HPCA; Calcium-binding protein BDR-1; BDR1; VILIP-3; Visinin-like protein 3
EINECS	Contact for details

Quality Control

Our Hippocalcin is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including purity assessment by HPLC, identity confirmation via mass spectrometry, and biological activity assays. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Protein Content (BCA)	≥ 90%
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Confirmed by calcium-binding assay
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.