Description

Ahnak Protein CAS NO 149176-44-3 is a high-purity, biologically active protein derived from the Ahnak gene product, a large scaffolding protein involved in cellular signaling and structural organization. This compound is critical for advanced life science research, enabling the study of calcium channel regulation, cell adhesion, and tumor suppressor mechanisms. It is an essential reagent for researchers and developers in the fields of molecular biology, oncology research, and diagnostic assay development, where precise protein-protein interactions are studied.

Application

• Biomedical Research: Used as a key antigen or standard in immunological assays (ELISA, Western Blot) to study its role in cellular processes.
• Cancer Research: Investigation of Ahnak's function as a tumor suppressor and its interactions with proteins like p53 and S100B in various cancer cell lines.
• Cardiovascular Studies: Research into the regulation of L-type calcium channels in cardiac and smooth muscle cells.
• Diagnostic Development: Serves as a critical component in the development of diagnostic kits targeting diseases associated with Ahnak protein dysregulation.
• Cell Biology: Study of cell membrane repair, cell migration, and cytoskeletal organization mechanisms.
• Pharmaceutical Screening: Utilized in high-throughput screening (HTS) platforms to identify potential therapeutic compounds that modulate Ahnak protein activity.

Basic Information

Item	Detail
Product Name	Ahnak Protein
CAS No.	149176-44-3
Molecular Formula	Contact for details
Molecular Weight	~700 kDa (approx., varies by isoform)
Synonyms	AHNAK Nucleoprotein; Desmoyokin; Neuroblast Differentiation-Associated Protein AHNAK; AHNAK1; KIAA1498; AHNAK Desmoyokin; Giant Protein AHNAK1; p700
EINECS	Contact for details

Quality Control

Our Ahnak Protein is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including SDS-PAGE for purity assessment, Western Blot for identity confirmation, and endotoxin level testing. Certificates of Analysis (COA) detailing purity, concentration, and biological activity are provided to ensure compliance with research-grade standards and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein aliquots should be stored at -80°C to prevent degradation. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Western Blot)	Conforms
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 95% of stated weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity	Assay-dependent; COA provided
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.