Description

Hmt2 Protein CAS NO 149147-63-7 is a high-purity recombinant protein of significant interest in advanced biochemical research and development. This protein plays a crucial role in the study of chromatin structure, histone modification, and epigenetic regulation, offering researchers a reliable tool for mechanistic investigations. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in proteomics, epigenetics, and novel therapeutic target discovery.

Application

• Epigenetics Research: Essential for studying histone methylation, chromatin remodeling, and gene expression regulation.
• Biochemical Assay Development: Used as a key component or standard in enzymatic activity assays and binding studies.
• Drug Discovery Screening: Serves as a target protein in high-throughput screening for inhibitors of histone-modifying enzymes.
• Proteomics and Protein Interaction Studies: Employed in pull-down assays, co-immunoprecipitation (Co-IP), and mass spectrometry to map protein-protein interaction networks.
• Antibody Production and Validation: Acts as an immunogen for generating specific antibodies or as a positive control for antibody validation.
• Structural Biology: Provides material for X-ray crystallography, NMR spectroscopy, and cryo-EM studies to elucidate protein structure and function.

Basic Information

Product Name	Hmt2 Protein
CAS No.	149147-63-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Histone Methyltransferase 2; HMT2; Protein Hmt2; Recombinant Hmt2; Histone-Lysine N-Methyltransferase Hmt2; SET Domain-Containing Protein 2; 149147-63-7
EINECS	Contact for details

Quality Control

Our Hmt2 Protein is manufactured under stringent quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is subjected to comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation, and functional activity assays. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Single band at expected molecular weight
Purity (HPLC)	≥ 95%
Protein Content	Determined by UV absorbance or Bradford assay
Biological Activity	Assessed by functional enzymatic assay
Endotoxin Level	< 1.0 EU/µg (for research-grade)
Solubility	Reconstitutes in suitable buffer (e.g., Tris-HCl, PBS)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.