Description

6-Hydroxy-5-(1-Pentofuranosyl-4'-Pyrmidin-2'-One)Dihydrothymine is a specialized nucleoside analog with significant potential in advanced biochemical research and development. This compound matters for its role as a key intermediate or reference standard in the synthesis of novel therapeutic agents and in the study of nucleic acid chemistry and enzymology. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on antiviral, anticancer, and molecular biology applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside-based antiviral or anticancer drug candidates.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies, particularly those involving DNA/RNA metabolism and repair pathways.
• Antiviral Agent Development: Investigated for its potential activity against viral polymerases and as a component in prodrug strategies.
• Molecular Probe Synthesis: Utilized in creating labeled compounds for diagnostic assays or imaging studies within cellular systems.
• Academic Research: Employed in universities and research institutes for fundamental studies in organic chemistry, medicinal chemistry, and chemical biology.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines for global clients.

Basic Information

Product Name	6-Hydroxy-5-(1-Pentofuranosyl-4'-Pyrmidin-2'-One)Dihydrothymine
CAS No.	149129-24-8
Molecular Formula	C14H18N2O8
Molecular Weight	342.30 g/mol
Synonyms	5,6-Dihydro-5-methyl-6-oxo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; Dihydrothymidine derivative; Modified Nucleoside; 6-Hydroxydihydrothymidine; 5-Methyl-6-oxodihydrouridine derivative
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-5-(1-Pentofuranosyl-4'-Pyrmidin-2'-One)Dihydrothymine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.