Description

3-[n-(7'-Nitrobenz-2'-Oxa-1',3'-Diazol-4'-Yl)Amino]Propanic Acid is a specialized fluorescent labeling reagent, a derivative of the widely used NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) fluorophore. This compound matters for its ability to covalently tag biomolecules, enabling sensitive detection and analysis in complex systems. It is primarily needed by researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic reagent industries for applications requiring high-sensitivity fluorescence.

Application

• Fluorescent Labeling of Biomolecules: Covalent conjugation to proteins, peptides, antibodies, and oligonucleotides for detection and quantification.
• Bioconjugation & Probe Synthesis: A key intermediate in the synthesis of custom fluorescent probes and sensors for cellular imaging.
• Life Science Research: Used in fluorescence microscopy, flow cytometry (FACS), and immunoassay development to track molecular localization and interactions.
• Pharmaceutical Analysis: Employed in assay development for drug discovery, including high-throughput screening (HTS) and pharmacokinetic studies.
• Diagnostic Reagent Manufacturing: Incorporated into the production of fluorescent diagnostic kits and lateral flow assays.
• Material Science: Potential use in creating fluorescently tagged polymers or surfaces for specialized analytical applications.

Basic Information

Product Name	3-[n-(7'-Nitrobenz-2'-Oxa-1',3'-Diazol-4'-Yl)Amino]Propanic Acid
CAS No.	149079-60-7
Molecular Formula	C12H10N4O6
Molecular Weight	306.23 g/mol
Synonyms	NBD-X; NBD-X Acid; 4-(7-Nitro-2,1,3-benzoxadiazol-4-ylamino)butyric Acid; 4-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl))aminobutyric Acid; 4-(NBD)aminobutyric Acid; 4-(NBD-amino)butyric Acid; 3-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino]Propanoic Acid; NBD Aminobutyric Acid
EINECS	Contact for details

Quality Control

Our 3-[n-(7'-Nitrobenz-2'-Oxa-1',3'-Diazol-4'-Yl)Amino]Propanic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for sensitive research and diagnostic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0 %
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.