Description

5,6-Dibromo-2,2-Difluorobenzo[D][1,3]Dioxole is a high-purity, multi-functional halogenated heterocyclic building block. This compound is valued for its unique molecular architecture, which combines bromine and fluorine substituents on a benzo[d][1,3]dioxole core, making it a versatile intermediate in advanced synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the difluoro and dibromo groups can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials due to its halogenated, electron-deficient aromatic system.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, allowing for the introduction of complex fragments.
• Fluorine Chemistry Research: A valuable compound for studying the effects of fluorine substitution on reactivity and physicochemical properties in medicinal and materials chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies engaged in custom synthesis and scale-up services for client-specific projects.

Basic Information

Product Name	5,6-Dibromo-2,2-Difluorobenzo[D][1,3]Dioxole
CAS No.	149045-80-7
Molecular Formula	C7H2Br2F2O2
Molecular Weight	315.90 g/mol
Synonyms	2,2-Difluoro-5,6-dibromobenzo[d][1,3]dioxole; 5,6-Dibromo-2,2-difluoro-1,3-benzodioxole; Benzo[d][1,3]dioxole, 5,6-dibromo-2,2-difluoro-; 149045-80-7; 2,2-Difluoro-5,6-dibromo-1,3-benzodioxole; 5,6-Dibromo-2,2-difluorobenzo-1,3-dioxole
EINECS	Contact for details

Quality Control

Our 5,6-Dibromo-2,2-Difluorobenzo[D][1,3]Dioxole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development and commercial projects requiring material that meets stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.