Description

2-Fluoro-5-Hydroxyphenylacetic Acid is a fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where the fluorine atom and phenolic hydroxyl group enable precise structural modifications. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, where the fluorine moiety can enhance bioavailability and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Bioconjugation & Probe Development: The carboxylic acid and hydroxyl functional groups make it suitable for coupling reactions in biochemical probe and linker synthesis.
• Academic & Contract Research: Employed in organic chemistry research for method development and exploring new fluorination chemistry pathways.
• Fine Chemical Manufacturing: Used in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	2-Fluoro-5-Hydroxyphenylacetic Acid
CAS No.	149029-89-0
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	2-(2-Fluoro-5-hydroxyphenyl)acetic Acid; (2-Fluoro-5-hydroxyphenyl)acetic Acid; 5-Hydroxy-2-fluorophenylacetic Acid; 2-Fluoro-5-hydroxybenzeneacetic Acid; α-Carboxy-3-fluoro-4-hydroxy toluene; 2-Fluoro-5-hydroxy-α-toluic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Hydroxyphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.