Description

n-Acetylgalactosamine Inhibitable Lectin 35-Kda Subunit, Entamoeba Histolytica is a highly specific protein subunit derived from the pathogenic amoeba *Entamoeba histolytica*. This lectin subunit is critical for research focused on understanding the molecular mechanisms of amoebic adhesion and host-pathogen interactions. It is an essential reagent for scientists in the fields of parasitology, infectious disease research, and glycobiology. The product is supplied to support the development of diagnostic tools and therapeutic strategies against amoebiasis.

Application

• Parasitology Research: Fundamental studies on the adhesion and virulence mechanisms of *Entamoeba histolytica*.
• Host-Pathogen Interaction Studies: Investigation of lectin-mediated binding to host cell surface glycans, particularly those containing GalNAc.
• Diagnostic Development: Used as a key antigen or capture molecule in the development of immunoassays and biosensors for detecting amoebic infection.
• Therapeutic Target Validation: Screening and evaluation of potential inhibitors targeting the GalNAc-inhibitable lectin pathway for anti-amoebic drug discovery.
• Glycobiology Research: A tool for studying carbohydrate-protein interactions and lectin specificity.
• Vaccine Research: Evaluation as a component or target in vaccine development against amoebiasis.

Basic Information

Product Name	n-Acetylgalactosamine Inhibitable Lectin 35-Kda Subunit, Entamoeba Histolytica
CAS No.	149024-46-4
Molecular Formula	Contact for details
Molecular Weight	~35 kDa (Subunit)
Synonyms	EhLectin 35 kDa Subunit; Gal/GalNAc-inhibitable lectin light subunit; *Entamoeba histolytica* lectin subunit; Amoebic lectin 35 kDa chain; Gal-lectin 35 kDa subunit; EhLG; 35-kDa lectin subunit; Contact for details
EINECS	Contact for details

Quality Control

Our n-Acetylgalactosamine Inhibitable Lectin 35-Kda Subunit is produced and handled under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot undergoes rigorous quality testing, including purity assessment, activity assays, and specificity checks. Certificates of Analysis (COA) detailing purity, concentration, and functional data are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. Handle as a biological material under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Single band at ~35 kDa
Purity (HPLC)	≥ 90%
Protein Content	≥ 95% (Biuret or Bradford)
Biological Activity	GalNAc-inhibitable hemagglutination or binding assay
Endotoxin Level	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.