Description

D,L-Threo-1-Phenyl-2-Hexadecanoylamino-3-Morpholino-1-Propanol Hcl is a synthetic, chiral amino alcohol derivative with a complex molecular architecture. This compound matters as a key intermediate or reference standard in advanced pharmaceutical research and development, particularly for investigating metabolic pathways and enzyme inhibition. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on metabolic disorders, lipid biochemistry, and glycosphingolipid synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex bioactive molecules and potential therapeutic agents.
• Biochemical Research: Used as a reference standard or inhibitor in studies of glucosylceramide synthase and related glycosphingolipid metabolic pathways.
• Enzyme Inhibition Studies: Acts as a tool compound for investigating the mechanism of action of enzymes involved in sphingolipid biosynthesis.
• Academic & Contract Research: Employed in university and CRO settings for fundamental research into lipid storage diseases and related disorders.
• Analytical Standard: Provides a high-purity standard for method development and quality control in analytical chemistry (HPLC, LC-MS).
• Preclinical Development: Utilized in early-stage drug discovery for proof-of-concept and pharmacological profiling studies.

Basic Information

Item	Detail
Product Name	D,L-Threo-1-Phenyl-2-Hexadecanoylamino-3-Morpholino-1-Propanol Hydrochloride
CAS No.	149022-18-4
Molecular Formula	C29H51ClN2O2
Molecular Weight	495.18 g/mol
Synonyms	DL-threo-1-Phenyl-2-palmitoylamino-3-morpholino-1-propanol hydrochloride; Phenyl-2-hexadecanoylamino-3-morpholino-1-propanol HCl; PDMP hydrochloride (DL-threo isomer); 1-Phenyl-2-hexadecanoylamino-3-morpholino-1-propanol HCl; DL-threo-PDMP HCl; Glucosylceramide synthase inhibitor (DL-threo form); (DL-threo)-1-Phenyl-2-hexadecanamido-3-morpholinopropan-1-ol hydrochloride
EINECS	Contact for details

Quality Control

Our D,L-Threo-1-Phenyl-2-Hexadecanoylamino-3-Morpholino-1-Propanol Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research use. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.