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Carbamic Acid, [(2R)-2,3-Dihydroxypropyl]-, 1,1-Dimethylethyl Ester (9Ci) CAS NO 148983-23-7


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CAS No.:148983-23-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Carbamic Acid, [(2R)-2,3-Dihydroxypropyl]-, 1,1-Dimethylethyl Ester (9Ci) is a chiral, protected amino alcohol derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and high-purity building block, enabling the precise construction of complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and fine chemical industries for applications such as the synthesis of active pharmaceutical ingredients (APIs), chiral ligands, and specialty polymers.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
  • Chiral Auxiliary & Ligand Synthesis: Used to construct sophisticated chiral ligands for asymmetric catalysis and as a precursor for chiral auxiliaries, enhancing stereoselectivity in synthetic routes.
  • Peptidomimetics & Bioactive Molecule Development: Serves as a protected glycerolamine moiety in the synthesis of peptidomimetics, enzyme inhibitors, and other bioactive compounds.
  • Polymer Chemistry: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties, such as hydrogels or drug delivery systems.
  • Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.
  • Agrochemical Research: Employed as an intermediate in the development of new, more selective herbicides and pesticides.

Basic Information

Product Name Carbamic Acid, [(2R)-2,3-Dihydroxypropyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No. 148983-23-7
Molecular Formula C9H19NO4
Molecular Weight 205.25 g/mol
Synonyms (2R)-2,3-Dihydroxypropyl tert-butylcarbamate; (R)-2,3-Dihydroxypropyl tert-butylcarbamate; tert-Butyl N-[(2R)-2,3-dihydroxypropyl]carbamate; (R)-1-(tert-Butoxycarbonylamino)-2,3-propanediol; (R)-3-(tert-Butoxycarbonylamino)-1,2-propanediol; (R)-Glycidol tert-butylcarbamate derivative; Boc-DAG-OH (commonly used abbreviation); (R)-Boc-aminopropanediol
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Quality Control

Our Carbamic Acid, [(2R)-2,3-Dihydroxypropyl]-, 1,1-Dimethylethyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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