Description

D2 Protein, Leishmania is a highly purified recombinant protein antigen derived from the protozoan parasite Leishmania. This protein is critical for research and diagnostic applications, specifically targeting the immune response to leishmaniasis. It is primarily utilized by biotechnology firms, academic research institutions, and diagnostic kit manufacturers engaged in tropical disease studies, vaccine development, and serological testing. The product is supplied with a focus on high batch-to-batch consistency and biological activity.

Application

• Serological Diagnostics: Key component in ELISA (Enzyme-Linked Immunosorbent Assay) and immunoblot kits for the detection of anti-Leishmania antibodies in patient sera.
• Vaccine Research & Development: Used as a target antigen in immunological assays to evaluate vaccine candidate efficacy and host immune responses.
• Basic Research: Employed in studies of host-parasite interactions, immunology, and the pathogenesis of leishmaniasis.
• Biomarker Discovery: Serves as a reference standard in proteomic and immunoproteomic studies to identify novel diagnostic markers.
• Quality Control Reagent: Used as a positive control in the manufacturing and validation of diagnostic assays to ensure test sensitivity and specificity.

Basic Information

Product Name	D2 Protein, Leishmania
CAS No.	148971-38-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Recombinant Leishmania D2 Protein; Leishmania D2 Antigen; D2 Recombinant Protein (Leishmania); D2 Antigen, Leishmania; Leishmania major D2 protein; D2 diagnostic antigen; D2 ELISA antigen; Parasite D2 Protein
EINECS	Contact for details

Quality Control

Our D2 Protein, Leishmania is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, verification of biological activity via immunoassay, and confirmation of identity. A Certificate of Analysis (COA) detailing lot-specific results is provided with every shipment to ensure traceability and compliance with your research or manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Aliquot upon receipt for single-use to maintain optimal activity.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (Immunoassay)	Positive reactivity with reference antisera
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 95% of total weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (ELISA)	Lot-specific titer provided on COA
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.