Description

Rec8 Protein CAS NO 148813-46-1 is a highly specialized recombinant protein crucial for the study of meiotic chromosome cohesion and segregation. This protein plays a fundamental role in the structural organization of chromosomes during cell division, making it an essential reagent for advanced life science research. It is primarily utilized by researchers and biopharmaceutical developers in the fields of molecular biology, genetics, and oncology to investigate cell cycle regulation, genome stability, and potential therapeutic targets.

Application

• Meiosis Research: Essential for in vitro studies of sister chromatid cohesion and homologous chromosome pairing during meiosis.
• Chromosome Biology: Used to investigate the molecular mechanisms of chromosome structure, dynamics, and segregation.
• Cancer Research: Applied in studies exploring the link between cohesion complex dysfunction and genomic instability in tumorigenesis.
• Biochemical Assay Development: Serves as a key component or standard in developing assays for protein-protein interactions and enzymatic activity.
• Antibody Production & Validation: Used as a high-purity antigen for generating and characterizing specific antibodies.
• Structural Biology: Provides material for X-ray crystallography or cryo-EM studies to determine protein structure and function.
• Educational & Diagnostic Tool: Employed in advanced academic settings and for developing diagnostic markers related to cell division errors.

Basic Information

Product Name	Rec8 Protein
CAS No.	148813-46-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Recombinant Rec8 Protein; Meiotic Recombination Protein REC8 Homolog; Cohesin Subunit Rec8; hRec8; REC8 Meiotic Recombination Protein; Chromosome-associated Protein Rec8; Meiotic Cohesin Rec8
EINECS	Contact for details

Quality Control

Our Rec8 Protein is produced under stringent conditions to ensure the highest levels of purity and biological activity. Each batch undergoes comprehensive analytical testing, including SDS-PAGE, HPLC, and functional activity assays, to guarantee consistency and performance. A detailed Certificate of Analysis (COA) documenting purity, concentration, endotoxin levels, and storage buffer is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to maintain stability.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Single band at expected molecular weight
Purity (HPLC)	≥ 95%
Protein Content	≥ 90% (by UV absorbance)
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Confirmed by functional assay
Solubility	Soluble in specified buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.