Description

Major Histocompatibility Complex-Binding Protein 2 is a specialized biochemical reagent with the CAS registry number 148770-78-9, playing a critical role in fundamental immunological research and development. This compound is essential for studying antigen presentation pathways and T-cell activation mechanisms. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on immunology, vaccine development, and therapeutic protein engineering.

Application

• Immunological Research: Used as a key reagent in studies of Major Histocompatibility Complex (MHC) class I and II antigen presentation pathways.
• T-Cell Activation Studies: Essential for in vitro assays investigating the mechanisms of T-cell receptor engagement and subsequent immune response initiation.
• Vaccine Development: Employed in the research and screening of novel vaccine candidates that aim to enhance or modulate specific immune responses.
• Autoimmune Disease Research: A vital tool for modeling and understanding the dysregulated immune responses characteristic of autoimmune disorders.
• Cancer Immunotherapy: Supports research into immune checkpoint modulation and the development of adoptive cell therapies, such as CAR-T cells.
• Biopharmaceutical Production: Can be used in quality control and process development for biologics that interact with the immune system.
• Diagnostic Assay Development: Serves as a component or standard in the development of high-sensitivity immunoassays and diagnostic kits.

Basic Information

Item	Detail
Product Name	Major Histocompatibility Complex-Binding Protein 2
CAS No.	148770-78-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MHC-Binding Protein 2; MHC-BP2; MHC Class II-Binding Protein; Antigen Presentation Protein; Immune Response Modulator Protein; T-Cell Activation Protein; HLA-Binding Protein 2 (Human Leukocyte Antigen); Immunological Research Reagent
EINECS	Contact for details

Quality Control

Our Major Histocompatibility Complex-Binding Protein 2 is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including purity assessment by HPLC and functional activity verification in relevant bioassays. A Certificate of Analysis (COA) detailing identity, purity, and specific activity is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive) and easily oxidized; for optimal preservation, it is recommended to store under an inert atmosphere such as argon or nitrogen after opening. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Protein Content (Biuret)	≥ 90.0%
Biological Activity	Assay-dependent; specified on COA
Endotoxin Level (LAL)	< 1.0 EU/mg
Solubility	Soluble in appropriate aqueous buffers
Moisture Content (KF)	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.