Description

1-Fluoro-2-(Methoxymethyl)Benzene is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a fluorine atom and a methoxymethyl ether group, makes it a valuable precursor for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists for applications in medicinal chemistry, material science, and the synthesis of specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Group Transformation: The methoxymethyl group can be used as a protective group or further modified, offering synthetic flexibility.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new reaction pathways in fluoroorganic chemistry.

Basic Information

Product Name	1-Fluoro-2-(Methoxymethyl)Benzene
CAS No.	148760-23-0
Molecular Formula	C9H11FO
Molecular Weight	154.18 g/mol
Synonyms	2-Fluorobenzyl Methyl Ether; (2-Fluorophenyl)methoxymethane; 1-Fluoro-2-(methoxymethyl)benzene; o-Fluorobenzyl Methyl Ether; 2-Fluoro-α-methoxytoluene; Fluorobenzyl Methyl Ether; Benzene, 1-fluoro-2-(methoxymethyl)-
EINECS	Contact for details

Quality Control

Our 1-Fluoro-2-(Methoxymethyl)Benzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting identity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are properly sealed. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.