Description

2-Furancarbonitrile,5-(Bromomethyl)-(9Ci) is a versatile brominated furan derivative, a key synthetic intermediate valued for its reactive bromomethyl group and nitrile functionality. This compound is critical for constructing complex molecular architectures in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in heterocyclic chemistry and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing functionalized furan rings.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the furan scaffold imparts specific biological activity.
• Material Science Research: Acts as a monomer or precursor for developing advanced polymers, liquid crystals, or organic electronic materials with unique properties.
• Cross-Coupling Reactions: The bromomethyl group makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Nucleophilic Substitution: The reactive bromine site allows for functionalization with various nucleophiles, enabling the introduction of amines, thiols, and other groups.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for catalysis or as a core structure in catalyst design for asymmetric synthesis.

Basic Information

Product Name	2-Furancarbonitrile,5-(Bromomethyl)-(9Ci)
CAS No.	148759-25-5
Molecular Formula	C6H4BrNO
Molecular Weight	186.01 g/mol
Synonyms	5-(Bromomethyl)-2-furonitrile; 5-(Bromomethyl)furan-2-carbonitrile; 2-Cyano-5-(bromomethyl)furan; 5-Bromomethyl-2-cyanofuran; 2-Furonitrile, 5-(bromomethyl)-; Bromomethylfuronitrile
EINECS	Contact for details

Quality Control

Our 2-Furancarbonitrile,5-(Bromomethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.