Description

Penicillin V β-Sulfoxide-D3 is a deuterated isotopologue of a key penicillin intermediate, specifically designed for advanced research and analytical applications. This compound is essential for use as an internal standard in mass spectrometry, enabling highly accurate quantification and metabolic studies of penicillin V and its derivatives. It is primarily utilized by pharmaceutical R&D laboratories, analytical chemists, and manufacturers of reference standards for quality control and method development.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of Penicillin V and related β-lactam antibiotics in complex biological and pharmaceutical matrices.
• Metabolic Pathway Tracing: Used in pharmacokinetic and drug metabolism studies to track the absorption, distribution, metabolism, and excretion (ADME) of penicillin compounds.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of degradation products and process-related impurities during drug development and stability testing.
• Reference Standard Manufacturing: Serves as a certified high-purity material for the production of analytical reference standards and calibration kits.
• Veterinary Drug Residue Analysis: Employed in food safety testing to monitor penicillin residues in meat, milk, and other animal products.
• Environmental Fate Studies: Facilitates research into the environmental persistence and breakdown pathways of antibiotic contaminants.

Basic Information

Product Name	Penicillin V β-Sulfoxide-D3
CAS No.	148680-07-3
Molecular Formula	C16H15D3N2O6S
Molecular Weight	369.39 g/mol (for D3 isotopologue)
Synonyms	Phenoxymethylpenicillin β-Sulfoxide-d3; Penicillin V Sulfoxide-d3; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid 4,4-Dioxide-d3; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-, 4,4-dioxide-d3; Pen V β-Sulfoxide-d3
EINECS	Contact for details

Quality Control

Our Penicillin V β-Sulfoxide-D3 is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (D3 content), chemical purity by HPLC, and identification by NMR and MS. We adhere to relevant industry standards for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. For long-term storage, consider storing desiccated at -20°C. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.