Description

Bicyclo[2.2.1]Heptane-2-Carbonitrile, 6-Hydroxy-6-Methyl-, (Exo,Exo)- (9Ci) is a highly functionalized, stereochemically defined bicyclic nitrile derivative, serving as a sophisticated chiral building block in advanced organic synthesis. Its rigid norbornane skeleton, combined with hydroxyl and nitrile functional groups, makes it a valuable precursor for pharmaceuticals, agrochemicals, and specialty materials where precise three-dimensional structure is critical. This compound is primarily sought by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Building block for creating advanced, stereoselective pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Monomer or cross-linking agent in the development of polymers with specific thermal or mechanical properties derived from the rigid norbornane core.
• Academic & Industrial R&D: Used in methodological studies and exploration of new synthetic pathways in organic chemistry.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Carbonitrile, 6-Hydroxy-6-Methyl-, (Exo,Exo)- (9Ci)
CAS No.	148638-09-9
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	6-Hydroxy-6-methylbicyclo[2.2.1]heptane-2-carbonitrile, exo,exo-; (1R,2S,4S,5R)-5-Hydroxy-5-methylbicyclo[2.2.1]heptane-2-carbonitrile; exo-6-Hydroxy-6-methyl-2-norbornanecarbonitrile; 6-Methyl-6-hydroxy-2-norbornanecarbonitrile (exo,exo-); Norbornane nitrile derivative; Bicyclo[2.2.1]heptane-2-carbonitrile, 6-hydroxy-6-methyl-, (1R,2S,4S,5R)-; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-2-Carbonitrile, 6-Hydroxy-6-Methyl-, (Exo,Exo)- is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (exo,exo- isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.