Description

(3Alpha,5Alpha,17Beta)-3-Hydroxyandrostan-17-Yl D-Glucopyranosiduronic Acid CAS NO 148616-25-5 is a high-purity steroid glucuronide conjugate, a crucial metabolite and reference standard in analytical and biochemical research. This compound is essential for scientists requiring precise and reliable materials for method development, validation, and metabolic profiling studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on endocrinology, drug metabolism, and pharmacokinetics (PK/ADME).

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the quantification and identification of steroid metabolites in complex biological matrices.
• Drug Metabolism & Pharmacokinetics (DMPK): Used in in vitro and in vivo studies to investigate the glucuronidation pathways of androgenic steroids.
• Clinical Research & Diagnostics: Employed in the development of high-sensitivity LC-MS/MS assays for hormonal profiling in clinical and anti-doping laboratories.
• Biochemical Research: Acts as a substrate or inhibitor in studies of UDP-glucuronosyltransferase (UGT) enzyme activity and specificity.
• Toxicology Studies: Applied in research examining the metabolic fate and excretion profiles of synthetic and endogenous steroids.
• Quality Control (QC) in Manufacturing: Used as an analytical standard to ensure the purity and consistency of related steroid-based pharmaceutical ingredients.

Basic Information

Product Name	(3Alpha,5Alpha,17Beta)-3-Hydroxyandrostan-17-Yl D-Glucopyranosiduronic Acid
CAS No.	148616-25-5
Molecular Formula	C25H38O9
Molecular Weight	482.57 g/mol
Synonyms	Androsterone glucuronide; 3α-Hydroxy-5α-androstan-17β-yl β-D-glucopyranosiduronic acid; 5α-Androstane-3α,17β-diol 17-glucuronide; 17β-Hydroxy-5α-androstan-3α-yl β-D-glucopyranosiduronic acid; Androstane-3α,17β-diol 17-O-β-D-glucuronide; Etiocholanolone glucuronide (related isomer); A-GLU; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of (3Alpha,5Alpha,17Beta)-3-Hydroxyandrostan-17-Yl D-Glucopyranosiduronic Acid is characterized using advanced analytical techniques, including HPLC, MS, and NMR, to guarantee identity, purity, and stability. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to strict quality management protocols suitable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the certificate of analysis. For long-term storage, consider storing desiccated at -20°C. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95.0% (Area %)
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.