Description

Ptx3 Protein CAS NO 148591-49-5 is a long pentraxin protein, a key component of the innate immune system with significant roles in inflammation and tissue remodeling. This high-purity protein is essential for advanced biomedical research and diagnostic development, offering researchers a reliable tool for studying cardiovascular disease, cancer, and other inflammatory pathologies. It is primarily utilized by biotechnology firms, pharmaceutical R&D departments, and clinical diagnostic manufacturers.

Application

• Biomarker Research & Diagnostic Assay Development: Used as a standard or calibrator in ELISA, chemiluminescence, and other immunoassays to quantify PTX3 levels in patient samples for cardiovascular risk assessment and cancer prognosis.
• Drug Discovery & Target Validation: Serves as a critical reagent in high-throughput screening (HTS) and functional studies to identify and validate novel therapeutic compounds targeting the PTX3 pathway.
• Inflammation and Immunology Studies: Employed in in vitro and in vivo models to investigate its role in modulating complement activation, pathogen recognition, and extracellular matrix organization.
• Cell Culture & Functional Assays: Used to study its effects on endothelial cell function, fibroblast activity, and macrophage polarization in various disease models.
• Quality Control & Reference Standard: Acts as a purity reference standard for the production and quality control of other recombinant proteins or antibody-based reagents.

Basic Information

Product Name	Ptx3 Protein
CAS No.	148591-49-5
Molecular Formula	CnHmNoOp (Contact for details)
Molecular Weight	~45 kDa (monomeric, glycosylated form). Contact for exact lot-specific data.
Synonyms	Pentraxin 3; TNF-inducible gene 14 protein (TSG-14); Long Pentraxin 3; PTX3; PTX3_HUMAN; Tumor necrosis factor-inducible gene 14 protein; Pentraxin-related protein PTX3
EINECS	Contact for details

Quality Control

Our Ptx3 Protein is produced under stringent conditions to ensure high biological activity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including SDS-PAGE, HPLC for purity assessment, and endotoxin level determination. Certificates of Analysis (COA) detailing purity, concentration, biological activity (where applicable), and sterility are provided and available upon request to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Upon reconstitution, aliquot and store at -80°C to avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Single band at ~45 kDa under reducing conditions
Purity (HPLC)	≥ 95%
Protein Content (UV Absorbance)	≥ 90% of label claim
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Functional Assay)	Contact for details
Solubility	Soluble in PBS or sterile water for injection

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.