Description

n-Dodecyl-B-D-Thiomaltopyranoside, Anagrade is a high-purity, non-ionic thioglycoside surfactant designed for demanding research and industrial applications. This specialized compound is valued for its ability to solubilize and stabilize membrane proteins without denaturation, making it a critical reagent in structural biology and biochemistry. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise and reliable detergents for protein characterization, crystallization, and formulation.

Application

• Membrane Protein Solubilization & Purification: A key detergent for extracting and purifying integral membrane proteins while maintaining their native structure and function for downstream analysis.
• Structural Biology Studies: Used in the preparation of samples for X-ray crystallography, cryo-electron microscopy (cryo-EM), and NMR spectroscopy to determine protein structures.
• Biophysical Characterization: Employed in assays studying protein-lipid interactions, ligand binding, and enzyme kinetics in membrane-mimetic environments.
• Pharmaceutical Formulation: Serves as an excipient in the development of biotherapeutic formulations to enhance stability and solubility of protein-based drugs.
• Viral Membrane Protein Research: Applied in the study of enveloped viruses to isolate and analyze viral envelope proteins for vaccine and antiviral drug development.
• Liposome & Nanodisc Preparation: Utilized in the creation of model membrane systems for studying membrane-associated processes and drug delivery vehicles.

Basic Information

Item	Details
Product Name	n-Dodecyl-B-D-Thiomaltopyranoside, Anagrade
CAS No.	148565-58-6
Molecular Formula	C24H46O10S
Molecular Weight	526.69 g/mol
Synonyms	n-Dodecyl-β-D-thiomaltoside; Dodecyl β-D-thiomaltopyranoside; DTM; n-Dodecyl-1-thio-β-D-maltopyranoside; Lauryl thiomaltoside; n-Dodecyl thiomaltoside; Anagrade DTM; 1-Thio-β-D-maltopyranoside dodecyl derivative
EINECS	Contact for details

Quality Control

Our Anagrade products are manufactured under a strict quality management system to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and critical impurities is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Critical Micelle Concentration (CMC)	0.15 - 0.20 mM (Typical in water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.