Description

Catabolite Gene Activator Protein-Like Protein is a specialized biochemical reagent designed for advanced life science research and development. This protein plays a critical role in studying gene regulation mechanisms, particularly those involving cyclic AMP (cAMP) receptor protein (CRP) homologs and transcription factor interactions. It is an essential tool for researchers in molecular biology, synthetic biology, and pharmaceutical discovery who require high-purity, well-characterized proteins for functional assays, structural studies, and pathway analysis.

Application

• Transcriptional Regulation Studies: Used as a model protein to investigate the mechanisms of catabolite repression and gene activation in bacterial and eukaryotic systems.
• Protein-DNA Interaction Assays: Essential for Electrophoretic Mobility Shift Assays (EMSAs), DNA footprinting, and other techniques to study specific DNA binding.
• Structural Biology Research: Serves as a target for X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy to elucidate three-dimensional structures and functional domains.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify small molecules or peptides that modulate its activity for potential therapeutic development.
• Enzyme and Cofactor Binding Studies: Utilized to analyze interactions with nucleotides like cAMP and other allosteric effectors.
• Educational and Diagnostic Kit Development: Incorporated into research kits for academic laboratories and as a component in diagnostic assay development for research use only (RUO).

Basic Information

Product Name	Catabolite Gene Activator Protein-Like Protein
CAS No.	148349-08-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CRP-like Protein; cAMP Receptor Protein-like Protein; Catabolite Activator Protein Homolog; Transcriptional Regulator CRP Homolog; CAP-like Protein; Gene Activator Protein Analog; Bacterial Transcription Factor Mimetic Protein
EINECS	Contact for details

Quality Control

Our Catabolite Gene Activator Protein-Like Protein is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including purity assessment by HPLC, confirmation of identity via mass spectrometry and/or peptide mapping, and evaluation of biological activity through functional assays. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize condensation and moisture uptake. Aliquot into working solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Protein Content (UV)	≥ 90%
Biological Activity (Assay)	Contact for details
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.